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H5N1 Influenza Vaccine Formulated with AS03(A) Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses
OBJECTIVE: Adjuvantation of an H5N1 split-virion influenza vaccine with AS03(A) substantially reduces the antigen dose required to produce a putatively protective humoral response and promotes cross-clade neutralizing responses. We determined the effect of adjuvantation on antibody persistence and B...
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Autors principals: | , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Springer US
2010
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132412/ https://ncbi.nlm.nih.gov/pubmed/21174144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9490-6 |
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