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The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation
Mycobacterium tuberculosis PtpA is a secreted effector protein that dephosphorylates several proteins in the host cell cytoplasm, such as p-JNK, p-p38, and p-VPS33B, leading to suppression of host innate immunity. Here we show that, in addition, PtpA enters the nucleus of host cells and regulates th...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557760/ https://ncbi.nlm.nih.gov/pubmed/28811474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00279-z |
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