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New potential eukaryotic substrates of the mycobacterial protein tyrosine phosphatase PtpA: hints of a bacterial modulation of macrophage bioenergetics state

The bacterial protein tyrosine phosphatase PtpA is a key virulence factor released by Mycobacterium tuberculosis in the cytosol of infected macrophages. So far only two unrelated macrophage components (VPS33B, GSK3α) have been identified as PtpA substrates. As tyrosine phosphatases are capable of us...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Margenat, Mariana, Labandera, Anne-Marie, Gil, Magdalena, Carrion, Federico, Purificação, Marcela, Razzera, Guilherme, Portela, María Magdalena, Obal, Gonzalo, Terenzi, Hernán, Pritsch, Otto, Durán, Rosario, Ferreira, Ana María, Villarino, Andrea
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390082/
https://ncbi.nlm.nih.gov/pubmed/25743628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08819
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