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Transcriptional and epigenetic regulation of T cell hyporesponsiveness
Naive CD8(+) T cells differentiate into effector and memory cytolytic T cells (CTLs) during an acute infection. In contrast, in scenarios of persistent antigen stimulation, such as chronic infections and cancer, antigen-specific CTLs show a gradual decrease in effector function, a phenomenon that ha...
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| Foilsithe in: | J Leukoc Biol |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Society for Leukocyte Biology
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557644/ https://ncbi.nlm.nih.gov/pubmed/28606939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2RI0317-097R |
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