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mTORC1 senses stresses: Coupling stress to proteostasis

Beyond protein synthesis and autophagy, emerging evidence has implicated mTORC1 in regulating protein folding and proteasomal degradation as well, highlighting its prominent role in cellular proteome homeostasis or proteostasis. In addition to growth signals, mTORC1 senses and responds to a wide arr...

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Detalles Bibliográficos
Publicado en:Bioessays
Main Authors: Su, Kuo-Hui, Dai, Chengkai
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557634/
https://ncbi.nlm.nih.gov/pubmed/28295473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600268
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