Epigenetic reprogramming converts human Wharton’s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

BACKGROUND: Lineage commitment of mesenchymal stem cells (MSCs) to cardiac differentiation is controlled by transcription factors that are regulated by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Here, we studied the differentiation of human Wharton’s jelly MSCs (WJ...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Bhuvanalakshmi, G., Arfuso, Frank, Kumar, Alan Prem, Dharmarajan, Arun, Warrier, Sudha
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557557/
https://ncbi.nlm.nih.gov/pubmed/28807014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0638-7
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