Epigenetic reprogramming converts human Wharton’s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

BACKGROUND: Lineage commitment of mesenchymal stem cells (MSCs) to cardiac differentiation is controlled by transcription factors that are regulated by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Here, we studied the differentiation of human Wharton’s jelly MSCs (WJ...

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Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Bhuvanalakshmi, G., Arfuso, Frank, Kumar, Alan Prem, Dharmarajan, Arun, Warrier, Sudha
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557557/
https://ncbi.nlm.nih.gov/pubmed/28807014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0638-7
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