Epigenetic reprogramming converts human Wharton’s jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

BACKGROUND: Lineage commitment of mesenchymal stem cells (MSCs) to cardiac differentiation is controlled by transcription factors that are regulated by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Here, we studied the differentiation of human Wharton’s jelly MSCs (WJ...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Bhuvanalakshmi, G., Arfuso, Frank, Kumar, Alan Prem, Dharmarajan, Arun, Warrier, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557557/
https://ncbi.nlm.nih.gov/pubmed/28807014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0638-7
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