Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4

Background: Identification of breast cancer stem cells as the chemo-resistant and tumor-initiating population represents an important milestone in approaching anticancer therapies. Targeting this minor subpopulation of chemo- and radio-resistant stem-like cells, termed as the cancer stem cells (CSCs...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bhuvanalakshmi, G., Basappa, Rangappa, Kanchugarakoppal S., Dharmarajan, Arun, Sethi, Gautam, Kumar, Alan P., Warrier, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357646/
https://ncbi.nlm.nih.gov/pubmed/28373842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00124
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