Mechanism of substrate translocation in an alternating access transporter

Transporters shuttle molecules across cell membranes by alternating among distinct conformational states. Fundamental questions remain about how transporters transition between states and how such structural rearrangements regulate substrate translocation. Here we capture the translocation process b...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Latorraca, Naomi R., Fastman, Nathan M., Venkatakrishnan, A. J., Frommer, Wolf B., Dror, Ron O., Feng, Liang
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557413/
https://ncbi.nlm.nih.gov/pubmed/28340354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.010
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