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A Pharmacodynamic Modeling and Simulation Study Identifying Gender Differences of Daily Olanzapine Dose and Dopamine D2-Receptor Occupancy
INTRODUCTION: Gender differences in treatment response rates for patients treated with antipsychotics are known. However, the literature lacks a pharmacodynamic model to allow for gender-based clinical trial simulations from modeling parameters for Olanzapine and dopamine D2 receptor occupancy. Thus...
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| Publicat a: | Nord J Psychiatry |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557349/ https://ncbi.nlm.nih.gov/pubmed/28486094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08039488.2017.1314011 |
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