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A Pharmacodynamic Modeling and Simulation Study Identifying Gender Differences of Daily Olanzapine Dose and Dopamine D2-Receptor Occupancy

INTRODUCTION: Gender differences in treatment response rates for patients treated with antipsychotics are known. However, the literature lacks a pharmacodynamic model to allow for gender-based clinical trial simulations from modeling parameters for Olanzapine and dopamine D2 receptor occupancy. Thus...

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Detaylı Bibliyografya
Yayımlandı:Nord J Psychiatry
Asıl Yazarlar: Eugene, Andy R., Masiak, Jolanta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557349/
https://ncbi.nlm.nih.gov/pubmed/28486094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08039488.2017.1314011
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