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Gender based Dosing of Metoprolol in the Elderly using Population Pharmacokinetic Modeling and Simulations
INTRODUCTION: This article seeks to clarify if gender-based differences occur in the pharmacokinetics of metoprolol in the elderly patients. There are a series of physiologic changes that occur in the elderly ranging from decreased hepatic blood flow to increased adiposity causing higher plasma conc...
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| Pubblicato in: | Int J Clin Pharmacol Toxicol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959610/ https://ncbi.nlm.nih.gov/pubmed/27468378 |
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