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Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-JUN) in the endothelium. Evidence suggests that polyphenolic antioxidants contained in the juice derived from the p...

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Main Authors: de Nigris, Filomena, Williams-Ignarro, Sharon, Lerman, Lilach O., Crimi, Ettore, Botti, Chiara, Mansueto, Gelsomina, D'Armiento, Francesco P., De Rosa, Gaetano, Sica, Vincenzo, Ignarro, Louis J., Napoli, Claudio
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC555721/
https://ncbi.nlm.nih.gov/pubmed/15781875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500998102
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