Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-JUN) in the endothelium. Evidence suggests that polyphenolic antioxidants contained in the juice derived from the p...

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Détails bibliographiques
Auteurs principaux: de Nigris, Filomena, Williams-Ignarro, Sharon, Lerman, Lilach O., Crimi, Ettore, Botti, Chiara, Mansueto, Gelsomina, D'Armiento, Francesco P., De Rosa, Gaetano, Sica, Vincenzo, Ignarro, Louis J., Napoli, Claudio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC555721/
https://ncbi.nlm.nih.gov/pubmed/15781875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500998102
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