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Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-JUN) in the endothelium. Evidence suggests that polyphenolic antioxidants contained in the juice derived from the p...

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Bibliografiska uppgifter
Huvudupphovsmän: de Nigris, Filomena, Williams-Ignarro, Sharon, Lerman, Lilach O., Crimi, Ettore, Botti, Chiara, Mansueto, Gelsomina, D'Armiento, Francesco P., De Rosa, Gaetano, Sica, Vincenzo, Ignarro, Louis J., Napoli, Claudio
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC555721/
https://ncbi.nlm.nih.gov/pubmed/15781875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500998102
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