Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-JUN) in the endothelium. Evidence suggests that polyphenolic antioxidants contained in the juice derived from the p...

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Bibliographic Details
Main Authors: de Nigris, Filomena, Williams-Ignarro, Sharon, Lerman, Lilach O., Crimi, Ettore, Botti, Chiara, Mansueto, Gelsomina, D'Armiento, Francesco P., De Rosa, Gaetano, Sica, Vincenzo, Ignarro, Louis J., Napoli, Claudio
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC555721/
https://ncbi.nlm.nih.gov/pubmed/15781875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500998102
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