Guanine α-carboxy nucleoside phosphonate (G-α-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency virus (HIV) and herpes viruses()

α-Carboxy nucleoside phosphonates (α-CNPs) are modified nucleotides that represent a novel class of nucleotide-competing reverse transcriptase (RT) inhibitors (NcRTIs). They were designed to act directly against HIV-1 RT without the need for prior activation (phosphorylation). In this respect, they...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Balzarini, Jan, Menni, Michael, Das, Kalyan, van Berckelaer, Lizette, Ford, Alan, Maguire, Nuala M., Liekens, Sandra, Boehmer, Paul E., Arnold, Eddy, Götte, Matthias, Maguire, Anita R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557014/
https://ncbi.nlm.nih.gov/pubmed/28390939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.04.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados