Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells

Tissue repair is a subset of a broad repertoire of interleukin-4 (IL-4)- and IL-13-dependent host responses during helminth infection. Here we show that IL-4 or IL-13 alone was not sufficient, but IL-4 or IL-13 together with apoptotic cells induced the tissue repair program in macrophages. Genetic a...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bosurgi, Lidia, Cao, Y. Grace, Cabeza-Cabrerizo, Mar, Tucci, Andrea, Hughes, Lindsey D., Kong, Yong, Weinstein, Jason S., Licona-Limon, Paula, Schmid, Edward T., Pelorosso, Facundo, Gagliani, Nicola, Craft, Joseph E., Flavell, Richard A., Ghosh, Sourav, Rothlin, Carla V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556699/
https://ncbi.nlm.nih.gov/pubmed/28495875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aai8132
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