REVEALING THE ACTIVATION PATHWAY FOR TMEM16A CHLORIDE CHANNELS FROM MACROSCOPIC CURRENTS AND KINETIC MODELS

TMEM16A (ANO1), the pore-forming subunit of calcium-activated chloride channels, regulates several physiological and pathophysiological processes such as smooth muscle contraction, cardiac and neuronal excitability, salivary secretion, tumour growth, and cancer progression. Gating of TMEM16A is comp...

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Détails bibliographiques
Publié dans:Pflugers Arch
Auteurs principaux: Contreras-Vite, Juan A., Cruz-Rangel, Silvia, De Jesús-Pérez, José J., Aréchiga Figueroa, Iván A., Rodríguez-Menchaca, Aldo A., Pérez-Cornejo, Patricia, Hartzell, H. Criss, Arreola, Jorge
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556394/
https://ncbi.nlm.nih.gov/pubmed/27138167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1830-9
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