SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots

We present SpotOn, a web server to identify and classify interfacial residues as Hot-Spots (HS) and Null-Spots (NS). SpotON implements a robust algorithm with a demonstrated accuracy of 0.95 and sensitivity of 0.98 on an independent test set. The predictor was developed using an ensemble machine lea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moreira, Irina S., Koukos, Panagiotis I., Melo, Rita, Almeida, Jose G., Preto, Antonio J., Schaarschmidt, Joerg, Trellet, Mikael, Gümüş, Zeynep H., Costa, Joaquim, Bonvin, Alexandre M. J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556074/
https://ncbi.nlm.nih.gov/pubmed/28808256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08321-2
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