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Delivery of large transgene cassettes by foamy virus vector
Viral vectors are effective tools in gene therapy, but their limited packaging capacity can be restrictive. Larger clinically-relevant vectors are needed. Foamy viruses have the largest genomes among mammalian retroviruses and their vectors have shown potential for gene therapy in preclinical studie...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5556010/ https://ncbi.nlm.nih.gov/pubmed/28808269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08312-3 |
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