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Delivery of large transgene cassettes by foamy virus vector

Viral vectors are effective tools in gene therapy, but their limited packaging capacity can be restrictive. Larger clinically-relevant vectors are needed. Foamy viruses have the largest genomes among mammalian retroviruses and their vectors have shown potential for gene therapy in preclinical studie...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sweeney, Nathan Paul, Meng, Jinhong, Patterson, Hayley, Morgan, Jennifer E., McClure, Myra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556010/
https://ncbi.nlm.nih.gov/pubmed/28808269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08312-3
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