Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector

Mesenchymal stromal cells (MSCs) hold great promise for regenerative medicine. Stable ex vivo gene transfer to MSCs could improve the outcome and scope of MSC therapy, but current vectors require multiple rounds of transduction, involve genotoxic viral promoters and/or the addition of cytotoxic cati...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Sweeney, Nathan Paul, Regan, Cathy, Liu, Jiahui, Galleu, Antonio, Dazzi, Francesco, Lindemann, Dirk, Rupar, Charles Anthony, McClure, Myra Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982542/
https://ncbi.nlm.nih.gov/pubmed/27133965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.91
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