LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

Acinetobacter baumannii ATCC 19606 can grow without lipid A, the major component of lipooligosaccharide. However, we previously reported that depletion of LpxH (the fourth enzyme in the lipid A biosynthetic pathway) prevented growth of this strain due to toxic accumulation of lipid A pathway interme...

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Bibliographic Details
Published in:mSphere
Main Authors: Wei, Jun-Rong, Richie, Daryl L., Mostafavi, Mina, Metzger, Louis E., Rath, Christopher M., Sawyer, William S., Takeoka, Kenneth T., Dean, Charles R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555675/
https://ncbi.nlm.nih.gov/pubmed/28815210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00199-17
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