Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

The lipid A moiety of lipopolysaccharide (LPS) is the main constituent of the outer leaflet of the Gram-negative bacterial outer membrane (OM) and is essential in many Gram-negative pathogens. An exception is Acinetobacter baumannii ATCC 19606, where mutants lacking enzymes occurring early in lipid...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Richie, Daryl L., Takeoka, Kenneth T., Bojkovic, Jade, Metzger, Louis E., Rath, Christopher M., Sawyer, William S., Wei, Jun-Rong, Dean, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985137/
https://ncbi.nlm.nih.gov/pubmed/27526195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160918
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