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Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis

Lipid A on the Gram-negative outer membrane (OM) is synthesized in the cytoplasm by the Lpx pathway and translocated to the OM by the Lpt pathway. Some Acinetobacter baumannii strains can tolerate the complete loss of lipopolysaccharide (LPS) resulting from the inactivation of early LPS pathway gene...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Bojkovic, Jade, Richie, Daryl L., Six, David A., Rath, Christopher M., Sawyer, William S., Hu, Qijun, Dean, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751815/
https://ncbi.nlm.nih.gov/pubmed/26668262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00639-15
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