RIG-I and IL-6 are negative-feedback regulators of STING induced by double-stranded DNA

The stimulator of interferon genes (STING) protein has emerged as a critical signal transduction molecule in the innate immune response. Sustained activation of the STING signaling induced by cytosolic DNA has been considered to be the cause of a variety of autoimmune diseases characterized by uncon...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Xueling, Yang, Jun, Na, Tao, Zhang, Kehua, Davidoff, Andrew M., Yuan, Bao-Zhu, Wang, Youchun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555650/
https://ncbi.nlm.nih.gov/pubmed/28806404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182961
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