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RIG-I and IL-6 are negative-feedback regulators of STING induced by double-stranded DNA
The stimulator of interferon genes (STING) protein has emerged as a critical signal transduction molecule in the innate immune response. Sustained activation of the STING signaling induced by cytosolic DNA has been considered to be the cause of a variety of autoimmune diseases characterized by uncon...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555650/ https://ncbi.nlm.nih.gov/pubmed/28806404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182961 |
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