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Progressive age-dependence and frequency difference in the effect of gap junctions on active cochlear amplification and hearing

Mutations of Connexin 26 (Cx26, GJB2), which is a predominant isoform in the cochlea, can induce high incidence of nonsyndromic hearing loss. We previously found that targeted-deletion of Cx26 in supporting Deiters cells and outer pillar cells in the cochlea can influence outer hair cell (OHC) elect...

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Pubblicato in:Biochem Biophys Res Commun
Autori principali: Zong, Liang, Chen, Jin, Zhu, Yan, Zhao, Hong-Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555358/
https://ncbi.nlm.nih.gov/pubmed/28552523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.05.137
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