Heat shock proteins stimulate APOBEC-3–mediated cytidine deamination in the hepatitis B virus

Apolipoprotein B mRNA-editing enzyme catalytic subunit 3 (APOBEC-3) enzymes are cytidine deaminases that are broadly and constitutively expressed. They are often up-regulated during carcinogenesis and candidate genes for causing the major single-base substitution in cancer-associated DNA mutations....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Chen, Zhigang, Eggerman, Thomas L., Bocharov, Alexander V., Baranova, Irina N., Vishnyakova, Tatyana G., Kurlander, Roger, Patterson, Amy P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555204/
https://ncbi.nlm.nih.gov/pubmed/28637869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.760637
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