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Quantitative Proteomic Analysis Reveals Similarities between Huntington’s Disease (HD) and Huntington’s Disease-Like 2 (HDL2) Human Brains

The pathogenesis of HD and HDL2, similar progressive neurodegenerative disorders caused by expansion mutations, remains incompletely understood. No systematic quantitative proteomics studies, assessing global changes in HD or HDL2 human brain, were reported. To address this deficit, we used a stable...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Ratovitski, Tamara, Chaerkady, Raghothama, Kammers, Kai, Stewart, Jacqueline C., Zavala, Anialak, Pletnikova, Olga, Troncoso, Juan C., Rudnicki, Dobrila D., Margolis, Russell L., Cole, Robert N., Ross, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555151/
https://ncbi.nlm.nih.gov/pubmed/27486686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00448
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