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Combination of Bevacizumab, Irinotecan and Temozolomide for Refractory or Relapsed Neuroblastoma: Results of a Phase II Study

BACKGROUND: The rationale for studying the combination of bevacizumab, irinotecan and temozolomide (BIT) in neuroblastoma is based on: (a) vascular endothelial growth factor (VEGF) expression is associated with an aggressive phenotype, (b) anti-VEGF antibody bevacizumab enhances irinotecan-mediated...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Modak, Shakeel, Kushner, Brian H., Basu, Ellen, Roberts, Stephen S., Cheung, Nai-Kong V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555116/
https://ncbi.nlm.nih.gov/pubmed/28111925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.26448
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