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PTEN as an effector in the signaling of antimigratory G protein-coupled receptor

PTEN, a tumor suppressor phosphatase, is important in the regulation of cell migration and invasion. Physiological regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) by cell surface receptors has not been described. Here, we show that the bioactive lipid sphingosine 1-phosp...

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Autori principali: Sanchez, Teresa, Thangada, Shobha, Wu, Ming-Tao, Kontos, Christopher D., Wu, Dianqing, Wu, Hong, Hla, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC555509/
https://ncbi.nlm.nih.gov/pubmed/15764699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409784102
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