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Predicting the Coupling Specificity of G-protein Coupled Receptors to G-proteins by Support Vector Machines

G-protein coupled receptors (GPCRs) represent one of the most important classes of drug targets for pharmaceutical industry and play important roles in cellular signal transduction. Predicting the coupling specificity of GPCRs to G-proteins is vital for further understanding the mechanism of signal...

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Bibliographic Details
Published in:Genomics Proteomics Bioinformatics
Main Authors: Guan, Cui-Ping, Jiang, Zhen-Ran, Zhou, Yan-Hong
Format: Artigo
Language:Inglês
Published: Elsevier 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173181/
https://ncbi.nlm.nih.gov/pubmed/16689694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1672-0229(05)03035-4
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