Lack of MTTP protein in pluripotent stem cell-derived hepatocytes/cardiomyocytes abolishes apoB secretion and increases cell stress

Abetalipoproteinemia (ABL) is an inherited disorder of lipoprotein metabolism resulting from mutations in Microsomal Triglyceride Transfer Protein (MTTP). In addition to the liver and intestine, MTTP is expressed in cardiomyocytes and cardiomyopathy has been reported in several ABL cases. Using indu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Liu, Ying, Conlon, Donna M., Bi, Xin, Slovik, Katherine J., Shi, Jianting, Edelstein, Hailey I., Millar, John S., Javaheri, Ali, Cuchel, Marina, Pashos, Evanthia E., Iqbal, Jahangir, Hussain, M. Mahmood, Hegele, Robert A., Yang, Wenli, Duncan, Stephen A., Rader, Daniel J., Morrisey, Edward E.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555078/
https://ncbi.nlm.nih.gov/pubmed/28514664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.04.064
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker