Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1

The lack of a cell culture system to support hepatitis C virus (HCV) replication has hampered studies of this frequent cause of chronic liver disease. However, pseudotyped retroviral particles (pp) bearing the HCV envelope glycoproteins have provided a different approach to HCV studies. We used geno...

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Bibliographic Details
Main Authors: Meunier, Jean-Christophe, Engle, Ronald E., Faulk, Kristina, Zhao, Ming, Bartosch, Birke, Alter, Harvey, Emerson, Suzanne U., Cosset, Francois-Loic, Purcell, Robert H., Bukh, Jens
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC555507/
https://ncbi.nlm.nih.gov/pubmed/15767578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501275102
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