FUNCTIONAL COMMUNICATION BETWEEN PKC-TARGETED CARDIAC TROPONIN I PHOSPHORYLATION SITES

Increased protein kinase C (PKC) activity is associated with heart failure, and can target multiple cardiac troponin I (cTnI) residues in myocytes, including S23/24, S43/45 and T144. In earlier studies, cTnI-S43D and/or -S45D augmented S23/24 and T144 phosphorylation, which suggested there is commun...

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發表在:Arch Biochem Biophys
Main Authors: Lang, Sarah E., Stevenson, Tamara K., Schatz, Tabea M, Biesiadecki, Brandon J., Westfall, Margaret V.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555030/
https://ncbi.nlm.nih.gov/pubmed/28587770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.05.019
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