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Independent Modulation of Contractile Performance by Cardiac Troponin I Ser43 and Ser45 in the Dynamic Sarcomere
Protein kinase C (PKC) targets cardiac troponin I (cTnI) S43/45 for phosphorylation in addition to other residues. During heart failure, cTnI S43/45 phosphorylation is elevated, and yet there is ongoing debate about its functional role due, in part, to the emergence of complex phenotypes in animal m...
Gardado en:
| Publicado en: | J Mol Cell Cardiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301988/ https://ncbi.nlm.nih.gov/pubmed/25481661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.11.022 |
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