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Suppression of viral infectivity through lethal defection

RNA viruses replicate with a very high error rate and give rise to heterogeneous, highly plastic populations able to adapt very rapidly to changing environments. Viral diseases are thus difficult to control because of the appearance of drug-resistant mutants, and it becomes essential to seek mechani...

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Main Authors: Grande-Pérez, Ana, Lázaro, Ester, Lowenstein, Pedro, Domingo, Esteban, Manrubia, Susanna C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC555496/
https://ncbi.nlm.nih.gov/pubmed/15767582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408871102
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