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Pathways to extinction: beyond the error threshold

Since the introduction of the quasispecies and the error catastrophe concepts for molecular evolution by Eigen and their subsequent application to viral populations, increased mutagenesis has become a common strategy to cause the extinction of viral infectivity. Nevertheless, the high complexity of...

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Detalhes bibliográficos
Main Authors: Manrubia, Susanna C., Domingo, Esteban, Lázaro, Ester
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880120/
https://ncbi.nlm.nih.gov/pubmed/20478889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0076
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