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Structure-Based Target-Specific Screening Leads to Small-Molecule CaMKII Inhibitors
Target-specific scoring methods are more commonly used to identify small-molecule inhibitors among compounds docked to a target of interest. Top candidates that emerge from these methods have rarely been tested for activity and specificity across a family of proteins. Here, we dock a chemical librar...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ChemMedChem |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554713/ https://ncbi.nlm.nih.gov/pubmed/28371191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600636 |
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