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Multi-invasions Are Recombination Byproducts That Induce Chromosomal Rearrangements

Inaccurate repair of broken chromosomes generates structural variants that can fuel evolution and inflict pathology. We describe a novel rearrangement mechanism in which translocation between intact chromosomes is induced by a lesion on a third chromosome. This multi-invasion-induced rearrangement (...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Piazza, Aurèle, Wright, William Douglass, Heyer, Wolf-Dietrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554464/
https://ncbi.nlm.nih.gov/pubmed/28781165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.052
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