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Successful metformin treatment of insulin resistance is associated with down-regulation of the kynurenine pathway
CONTEXT: An extensive body of literature indicates a relationship between insulin resistance and the up-regulation of the kynurenine pathway, i.e. the preferential conversion of tryptophan to kynurenine, with subsequent overproduction of diabetogenic downstream metabolites, such as kynurenic acid. C...
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| Udgivet i: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554450/ https://ncbi.nlm.nih.gov/pubmed/28478038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.04.155 |
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