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Metformin enhances insulin signalling in insulin-dependent and -independent pathways in insulin resistant muscle cells

1. Metformin lowers blood glucose levels in type 2 diabetic patients. To evaluate the insulin sensitizing action of metformin on skeletal muscle cells, we have used C2C12 skeletal muscle cells differentiated in chronic presence or absence of insulin. 2. Metformin was added during the last 24 h of di...

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Hlavní autoři: Kumar, Naresh, Dey, Chinmoy S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573500/
https://ncbi.nlm.nih.gov/pubmed/12237252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704878
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