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Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

BACKGROUND: Identification of genes whose basal mRNA expression predicts the sensitivity of tumor cells to cytotoxic treatments can play an important role in individualized cancer medicine. It enables detailed characterization of the mechanism of action of drugs. Furthermore, screening the expressio...

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Publicado en:Genome Biol
Autores principales: Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554409/
https://ncbi.nlm.nih.gov/pubmed/28800781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1282-3
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