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Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

BACKGROUND: Identification of genes whose basal mRNA expression predicts the sensitivity of tumor cells to cytotoxic treatments can play an important role in individualized cancer medicine. It enables detailed characterization of the mechanism of action of drugs. Furthermore, screening the expressio...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554409/
https://ncbi.nlm.nih.gov/pubmed/28800781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1282-3
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