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Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance

BACKGROUND: Identification of genes whose basal mRNA expression predicts the sensitivity of tumor cells to cytotoxic treatments can play an important role in individualized cancer medicine. It enables detailed characterization of the mechanism of action of drugs. Furthermore, screening the expressio...

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發表在:Genome Biol
Main Authors: Emad, Amin, Cairns, Junmei, Kalari, Krishna R., Wang, Liewei, Sinha, Saurabh
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554409/
https://ncbi.nlm.nih.gov/pubmed/28800781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1282-3
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