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Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer
P-glycoprotein (P-gp) is a drug transporter that effluxes chemotherapeutic drugs and is implicated in the development of resistance of cancer cells to chemotherapeutic drugs. To date, no drug has been approved to inhibit P-gp and restore chemotherapy efficacy. Moreover, majority of the reported inhi...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554262/ https://ncbi.nlm.nih.gov/pubmed/28801675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08062-2 |
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