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T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences
Diversity of T cell receptor (TCR) repertoires, generated by somatic DNA rearrangements, is central to immune system function. However, the level of sequence similarity of TCR repertoires within and between species has not been characterized. Using network analysis of high-throughput TCR sequencing...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5553937/ https://ncbi.nlm.nih.gov/pubmed/28731407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22057 |
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