Feature selection using a one dimensional naïve Bayes’ classifier increases the accuracy of support vector machine classification of CDR3 repertoires

MOTIVATION: Somatic DNA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. How this diversity captures antigen specificity remains incompletely understood. In this study we use high throughput sequencing to compa...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Cinelli, Mattia, Sun, , Yuxin, Best, Katharine, Heather, James M, Reich-Zeliger, Shlomit, Shifrut, Eric, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Discovery Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860388/
https://ncbi.nlm.nih.gov/pubmed/28073756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw771
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