AUTOGENOUS CONTROL OF 5′TOP mRNA STABILITY BY 40S RIBOSOMES

Ribosomal protein (RP) expression in higher eukaryotes is regulated translationally, through the 5′TOP sequence. This mechanism evolved to more rapidly produce RPs on demand in different tissues. Here we show that 40S ribosomes, in a complex with mRNA binding protein LARP1, selectively stabilize 5′T...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cell
मुख्य लेखकों: Gentilella, Antonio, Morón-Duran, Francisco D., Fuentes, Pedro, Zweig-Rocha, Guilherme, Riaño-Canalias, Ferran, Pelletier, Joffrey, Ruiz, Marta, Turón, Gemma, Castaño, Julio, Tauler, Albert, Bueno, Clara, Menéndez, Pablo, Kozma, Sara C., Thomas, George
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553558/
https://ncbi.nlm.nih.gov/pubmed/28673543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.06.005
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