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Meta-C–H Arylation and Alkylation of Benzylsulfonamide Enabled by a Pd(II)/Isoquinoline Catalyst

Palladium(II)-catalyzed meta-C–H arylation and alkylation of benzylsulfonamide using 2-carbomethoxynorbornene (NBE-CO(2)Me) as a transient mediator are realized using a newly developed electron-deficient directing group and isoquinoline as a ligand. This protocol features broad substrate scope and e...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Cheng, Guolin, Wang, Peng, Yu, Jin-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553125/
https://ncbi.nlm.nih.gov/pubmed/28516518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201704411
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