NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology

Autosomal recessive polycystic kidney disease (ARPKD) is an important childhood nephropathy, occurring 1 in 20,000 live births. The major clinical phenotypes are expressed in the kidney with dilatation of the collecting ducts, systemic hypertension, and progressive renal insufficiency, and in the li...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kaimori, Jun-ya, Lin, Cheng-Chao, Outeda, Patricia, Garcia-Gonzalez, Miguel A., Menezes, Luis F., Hartung, Erum A., Li, Ao, Wu, Guanqing, Fujita, Hideaki, Sato, Yasunori, Nakanuma, Yasuni, Yamamoto, Satoko, Ichimaru, Naotsugu, Takahara, Shiro, Isaka, Yoshitaka, Watnick, Terry, Onuchic, Luiz F., Guay-Woodford, Lisa M., Germino, Gregory G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552802/
https://ncbi.nlm.nih.gov/pubmed/28798345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08284-4
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items