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TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice

Recent studies have shown that overexpression of tonicity-responsive enhancer binding protein (TonEBP) is associated with many inflammatory diseases, including diabetes mellitus, which causes neuroinflammation in the hippocampus as well as hepatic steatosis. However, the exact mechanism in diabetic...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lee, Jong Youl, Jeong, Eun Ae, Kim, Kyung Eun, Yi, Chin-ok, Jin, Zhen, Lee, Jung Eun, Lee, Dong Hoon, Kim, Hyun Joon, Kang, Sang Soo, Cho, Gyeong Jae, Choi, Wan Sung, Choi, Soo Youn, Kwon, H. Moo, Roh, Gu Seob
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552681/
https://ncbi.nlm.nih.gov/pubmed/28798347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08319-w
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